Burkholderia vietnamiensis G4, Bcep1808_4472 (bceN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia vietnamiensis G4
GCF_000016205.1|latest
Locus Tag
Bcep1808_4472
NCBI Locus TagBCEP1808_RS22345
Name
bceN
Replicon chromosome 2
Genomic location 1311103 - 1312149 (- strand)

Cross-References

RefSeq WP_011881771.1
GI 134293166
Entrez 4950690
GI 134293166
INSDC ABO57437.1
NCBI Locus Tag BCEP1808_RS22345
NCBI Old Locus Tag Bcep1808_4472
RefSeq WP_011881771.1
UniParc UPI00003A54BA
UniProtKB Acc A4JMD4
UniProtKB ID A4JMD4_BURVG
UniRef100 UniRef100_A4JMD4
UniRef50 UniRef50_Q2T7G0
UniRef90 UniRef90_B4EFL2

Product

Feature Type CDS
Coding Frame 1
Product Name
BceN
Product Name Confidence: Class 2
Synonyms GDP-mannose 4,6-dehydratase
Evidence for Translation
Charge (pH 7) -1.61
Kyte-Doolittle Hydrophobicity Value -0.327
Molecular Weight (kDa) 38913.8
Isoelectric Point (pI) 6.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 610 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003102 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcep1808_4472
Search term: bceN
Search term: BceN

Human Homologs

Ensembl 97, assembly GRCh38.p12
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value: 1.1e-99
Percent Identity: 53.3

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863