Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS02225 (htrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0034605 cellular response to heat
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
17220310 Reviewed by curator
Biological Process GO:0071472 cellular response to salt stress
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
17220310 Reviewed by curator
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50156
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006508 proteolysis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02037
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004252 serine-type endopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02037
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00987 PDZ_serine_protease 298 387 8.624E-26
SUPERFAMILY SSF50156 IPR036034 PDZ superfamily 408 491 3.02E-18
Pfam PF13180 PDZ domain IPR001478 PDZ domain 299 389 5.5E-19
Pfam PF13365 Trypsin-like peptidase domain 126 259 2.1E-36
PRINTS PR00834 HtrA/DegQ protease family signature IPR001940 Peptidase S1C 252 269 1.0E-52
ProSiteProfiles PS50106 PDZ domain profile. IPR001478 PDZ domain 289 380 15.019
Gene3D G3DSA:2.40.10.120 54 292 1.3E-80
Gene3D G3DSA:2.30.42.10 293 399 1.2E-28
PRINTS PR00834 HtrA/DegQ protease family signature IPR001940 Peptidase S1C 338 350 1.0E-52
PRINTS PR00834 HtrA/DegQ protease family signature IPR001940 Peptidase S1C 156 176 1.0E-52
Pfam PF17820 PDZ domain IPR041489 PDZ domain 6 435 479 1.3E-14
SUPERFAMILY SSF50494 IPR009003 Peptidase S1, PA clan 53 289 1.02E-65
PRINTS PR00834 HtrA/DegQ protease family signature IPR001940 Peptidase S1C 230 247 1.0E-52
TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do IPR011782 Peptidase S1C, Do 56 489 1.0E-152
PRINTS PR00834 HtrA/DegQ protease family signature IPR001940 Peptidase S1C 135 147 1.0E-52
ProSiteProfiles PS50106 PDZ domain profile. IPR001478 PDZ domain 394 484 12.888
SUPERFAMILY SSF50156 IPR036034 PDZ superfamily 256 380 1.08E-26
CDD cd00987 PDZ_serine_protease 408 491 2.3079E-19
PRINTS PR00834 HtrA/DegQ protease family signature IPR001940 Peptidase S1C 196 220 1.0E-52
SMART SM00228 IPR001478 PDZ domain 408 484 1.1E-11
Gene3D G3DSA:2.30.42.10 408 491 4.5E-18
SMART SM00228 IPR001478 PDZ domain 298 380 1.8E-17

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.