Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS32100 (zmpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008233 peptidase activity
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
12904566 Reviewed by curator
Molecular Function GO:0004222 metalloendopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02868
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006508 proteolysis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00730
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif IPR011096 FTP domain 70 116 1.4E-14
SUPERFAMILY SSF55486 219 564 4.4E-63
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 464 480 4.9E-15
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 396 407 4.9E-15
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 338 358 4.9E-15
Coils Coil 564 565 -
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 375 391 4.9E-15
Gene3D G3DSA:1.10.390.10 IPR027268 Peptidase M4/M1, CTD superfamily 389 564 1.0E-46
Pfam PF01447 Thermolysin metallopeptidase, catalytic domain IPR013856 Peptidase M4 domain 222 384 1.9E-35
Gene3D G3DSA:3.10.170.10 221 388 5.2E-36
Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain IPR001570 Peptidase M4, C-terminal 387 564 3.1E-49
CDD cd09597 M4_TLP 256 564 6.67143E-100

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.